"We are a nimble, entrepreneurial, technology development company purpose-built to move ideas quickly from initial concept to market," says Cynthia Richard, Founder and President of Directed Genomics. "Partnering with NEB allows us to leverage an extensive knowledge-base of enzyme activities, best-in-class manufacturing practices and their global commercial footprint."

The first joint product concept to be developed as a result of this partnership, which is being presented at the American Society of Human Genetics (ASHG) annual conference in San Diego, California, October 18-22nd, is a target enrichment technology that combines enrichment with NGS library construction into a single, seamless protocol. The approach is scalable and enables the conversion of small amounts of genomic DNA into sequence-ready libraries, in about six hours. Enrichment is also highly specific, enabling greater coverage of target regions with fewer sequencing reads than other currently-available target-capture methods.

"Though still in development, the technical data produced to date is impressive. We look forward to further developing this method and applying it in a variety of research and translational workflows," commented Theodore Davis, Director of Applications and Product Development at NEB.

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